Understanding the Global Regulatory Environment for Melatonin Supplements

Melatonin, a hormone that regulates sleep-wake cycles, has gained significant popularity as a dietary supplement for improving sleep quality and managing circadian rhythm disorders. The regulatory status of melatonin varies widely across the globe, reflecting differences in public health policies, scientific assessments of safety and efficacy, and cultural attitudes towards supplements. This article explores the regulatory frameworks governing the use of melatonin in major health supplement markets, including the United States, the European Union, Canada, Australia, China, Japan, and Singapore.